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Mutational analysis of Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in the interior division of Sabah, Malaysia

BACKGROUND: The sulphadoxine/pyrimethamine (SDX/PYR) combination had been chosen to treat uncomplicated falciparum malaria in Malaysia for more than 30 years. Non-silent mutations in dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes are responsible for the resistance to pyrime...

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Bibliografiset tiedot
Päätekijät: Lau, Tiek Ying, Sylvi, Mersumpin, William, Timothy
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029390/
https://ncbi.nlm.nih.gov/pubmed/24321120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-445
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