Linking altered central pain processing and genetic polymorphism to drug efficacy in chronic low back pain

BACKGROUND: Inability to predict the therapeutic effect of a drug in individual pain patients prolongs the process of drug and dose finding until satisfactory pharmacotherapy can be achieved. Many chronic pain conditions are associated with hypersensitivity of the nervous system or impaired endogeno...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Pharmacol Toxicol
Auteurs principaux: Siegenthaler, Andreas, Schliessbach, Jürg, Vuilleumier, Pascal H., Juni, Peter, Zeilhofer, Hanns U., Arendt-Nielsen, Lars, Curatolo, Michele
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Study Protocol
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574129/
https://ncbi.nlm.nih.gov/pubmed/26376691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-015-0023-z
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