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Evaluation of Anti-Hyperalgesic and Analgesic Effects of Two Benzodiazepines in Human Experimental Pain: A Randomized Placebo-Controlled Study

BACKGROUND AND AIMS: Compounds that act on GABA-receptors produce anti-hyperalgesia in animal models, but little is known on their effects in humans. The aim of this study was to explore the potential usefulness of GABA-agonism for the control of pain in humans. Two agonists at the benzodiazepine-bi...

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Библиографические подробности
Главные авторы: Vuilleumier, Pascal H., Besson, Marie, Desmeules, Jules, Arendt-Nielsen, Lars, Curatolo, Michele
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598812/
https://ncbi.nlm.nih.gov/pubmed/23554851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043896
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