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Linking altered central pain processing and genetic polymorphism to drug efficacy in chronic low back pain

BACKGROUND: Inability to predict the therapeutic effect of a drug in individual pain patients prolongs the process of drug and dose finding until satisfactory pharmacotherapy can be achieved. Many chronic pain conditions are associated with hypersensitivity of the nervous system or impaired endogeno...

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Detalhes bibliográficos
Publicado no:BMC Pharmacol Toxicol
Main Authors: Siegenthaler, Andreas, Schliessbach, Jürg, Vuilleumier, Pascal H., Juni, Peter, Zeilhofer, Hanns U., Arendt-Nielsen, Lars, Curatolo, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574129/
https://ncbi.nlm.nih.gov/pubmed/26376691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-015-0023-z
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