BIDCHIPS: bias decomposition and removal from ChIP-seq data clarifies true binding signal and its functional correlates

BACKGROUND: Unraveling transcriptional regulatory networks is a central problem in molecular biology and, in this quest, chromatin immunoprecipitation and sequencing (ChIP-seq) technology has given us the unprecedented ability to identify sites of protein-DNA binding and histone modification genome...

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Vydáno v:Epigenetics Chromatin
Hlavní autoři: Ramachandran, Parameswaran, Palidwor, Gareth A., Perkins, Theodore J.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574076/
https://ncbi.nlm.nih.gov/pubmed/26388941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-015-0028-2
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