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RECAP reveals the true statistical significance of ChIP-seq peak calls

MOTIVATION: Chromatin Immunopreciptation (ChIP)-seq is used extensively to identify sites of transcription factor binding or regions of epigenetic modifications to the genome. A key step in ChIP-seq analysis is peak calling, where genomic regions enriched for ChIP versus control reads are identified...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Chitpin, Justin G, Awdeh, Aseel, Perkins, Theodore J
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761936/
https://ncbi.nlm.nih.gov/pubmed/30824903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz150
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