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Notch1 activation or loss promotes HPV-induced oral tumorigenesis

Viral oncogene expression is insufficient for neoplastic transformation of human cells, so HPV-associated cancers will also rely upon mutations in cellular oncogenes and tumor suppressors. However, it has been difficult so far to distinguish incidental mutations without phenotypic impact from causal...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Zhong, Rong, Bao, Riyue, Faber, Pieter W., Bindokas, Vytautas P., Bechill, John, Lingen, Mark W., Spiotto, Michael T.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573897/
https://ncbi.nlm.nih.gov/pubmed/26294213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0199
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