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Notch1 activation or loss promotes HPV-induced oral tumorigenesis
Viral oncogene expression is insufficient for neoplastic transformation of human cells, so HPV-associated cancers will also rely upon mutations in cellular oncogenes and tumor suppressors. However, it has been difficult so far to distinguish incidental mutations without phenotypic impact from causal...
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Udgivet i: | Cancer Res |
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Main Authors: | , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2015
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4573897/ https://ncbi.nlm.nih.gov/pubmed/26294213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0199 |
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