Maspin Expression in Prostate Tumor Cells Averts Stemness and Stratifies Drug Sensitivity

Future curative cancer chemotherapies have to overcome tumor cell heterogeneity and plasticity. To test the hypothesis that the tumor suppressor maspin may reduce microenvironment-dependent prostate tumor cell plasticity and thereby modulate drug sensitivity, we established a new schematic combinati...

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Bibliografiska uppgifter
I publikationen:Cancer Res
Huvudupphovsmän: Bernardo, M. Margarida, Kaplun, Alexander, Dzinic, Sijana H., Li, Xiaohua, Irish, Jonathan, Mujagic, Adelina, Jakupovic, Benjamin, Back, Jessica B., Van Buren, Eric, Han, Xiang, Dean, Ivory, Chen, Yong Q., Heath, Elisabeth, Sakr, Wael, Sheng, Shijie
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573892/
https://ncbi.nlm.nih.gov/pubmed/26208903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0234
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