Maspin Expression in Prostate Tumor Cells Averts Stemness and Stratifies Drug Sensitivity

Future curative cancer chemotherapies have to overcome tumor cell heterogeneity and plasticity. To test the hypothesis that the tumor suppressor maspin may reduce microenvironment-dependent prostate tumor cell plasticity and thereby modulate drug sensitivity, we established a new schematic combinati...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Bernardo, M. Margarida, Kaplun, Alexander, Dzinic, Sijana H., Li, Xiaohua, Irish, Jonathan, Mujagic, Adelina, Jakupovic, Benjamin, Back, Jessica B., Van Buren, Eric, Han, Xiang, Dean, Ivory, Chen, Yong Q., Heath, Elisabeth, Sakr, Wael, Sheng, Shijie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573892/
https://ncbi.nlm.nih.gov/pubmed/26208903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0234
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