The secretion and biological function of tumor suppressor maspin as an exosome cargo protein

Maspin is an epithelial-specific tumor suppressor shown to exert its biological effects as an intracellular, cell membrane-associated, and secreted free molecule. A recent study suggests that upon DNA-damaging g-irradiation, tumor cells can secrete maspin as an exosome-associated protein. To date, t...

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Vydáno v:Oncotarget
Hlavní autoři: Dean, Ivory, Dzinic, Sijana H, Bernardo, M. Margarida, Zou, Yi, Kimler, Vickie, Li, Xiaohua, Kaplun, Alexander, Granneman, James, Mao, Guangzhao, Sheng, Shijie
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352381/
https://ncbi.nlm.nih.gov/pubmed/28009978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13302
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