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A negative loop within the nuclear pore complex controls global chromatin organization

The nuclear pore complex (NPC) tethers chromatin to create an environment for gene regulation, but little is known about how this activity is regulated to avoid excessive tethering of the genome. Here we propose a negative regulatory loop within the NPC controlling the chromatin attachment state, in...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Breuer, Manuel, Ohkura, Hiroyuki
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573852/
https://ncbi.nlm.nih.gov/pubmed/26341556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.264341.115
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