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Chromatin organization at the nuclear pore favours HIV replication

The molecular mechanisms that allow HIV to integrate into particular sites of the host genome are poorly understood. Here we tested if the nuclear pore complex (NPC) facilitates the targeting of HIV integration by acting on chromatin topology. We show that the integrity of the nuclear side of the NP...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Lelek, Mickaël, Casartelli, Nicoletta, Pellin, Danilo, Rizzi, Ermanno, Souque, Philippe, Severgnini, Marco, Di Serio, Clelia, Fricke, Thomas, Diaz-Griffero, Felipe, Zimmer, Christophe, Charneau, Pierre, Di Nunzio, Francesca
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366494/
https://ncbi.nlm.nih.gov/pubmed/25744187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7483
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