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Chromatin organization at the nuclear pore favours HIV replication

The molecular mechanisms that allow HIV to integrate into particular sites of the host genome are poorly understood. Here we tested if the nuclear pore complex (NPC) facilitates the targeting of HIV integration by acting on chromatin topology. We show that the integrity of the nuclear side of the NP...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Lelek, Mickaël, Casartelli, Nicoletta, Pellin, Danilo, Rizzi, Ermanno, Souque, Philippe, Severgnini, Marco, Di Serio, Clelia, Fricke, Thomas, Diaz-Griffero, Felipe, Zimmer, Christophe, Charneau, Pierre, Di Nunzio, Francesca
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366494/
https://ncbi.nlm.nih.gov/pubmed/25744187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7483
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