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Histone Deacetylase 10 Regulates the Cell Cycle G(2)/M Phase Transition via a Novel Let-7–HMGA2–Cyclin A2 Pathway
Histone deacetylase (HDAC) inhibition leads to cell cycle arrest in G(1) and G(2), suggesting HDACs as therapeutic targets for cancer and diseases linked to abnormal cell growth and proliferation. Many HDACs are transcriptional repressors. Some may alter cell cycle progression by deacetylating histo...
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| Gepubliceerd in: | Mol Cell Biol |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4573710/ https://ncbi.nlm.nih.gov/pubmed/26240284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00400-15 |
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