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Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication

The protein deacetylase SIRT1 (Sirtuin 1) regulates many cellular processes, including cell-cycle progression, DNA damage response, and metabolism. Although the centrosome is a key regulator of cell-cycle progression and genome stability, little is known concerning SIRT1 controlled centrosome-associ...

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Publicat a:Cell Rep
Autors principals: Ling, Hongbo, Peng, Lirong, Wang, Jianbo, Rahhal, Raneen, Seto, Edward
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814291/
https://ncbi.nlm.nih.gov/pubmed/30517871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.11.025
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