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Regulation of Cyclin B2 Expression and Cell Cycle G(2)/M Transition by Menin

Multiple endocrine neoplasia type 1 (MEN1) results from mutations in tumor suppressor gene Men1, which encodes nuclear protein menin. Menin up-regulates certain cyclin-dependent kinase inhibitors through increasing histone H3 lysine 4 (H3K4) methylation and inhibits G(0)/G(1) to S phase transition....

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Hlavní autoři: Wu, Ting, Zhang, Xiuli, Huang, Xiaohua, Yang, Yuqing, Hua, Xianxin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881754/
https://ncbi.nlm.nih.gov/pubmed/20404349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106575
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