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Histone Deacetylase 10 Regulates the Cell Cycle G(2)/M Phase Transition via a Novel Let-7–HMGA2–Cyclin A2 Pathway

Histone deacetylase (HDAC) inhibition leads to cell cycle arrest in G(1) and G(2), suggesting HDACs as therapeutic targets for cancer and diseases linked to abnormal cell growth and proliferation. Many HDACs are transcriptional repressors. Some may alter cell cycle progression by deacetylating histo...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Li, Yixuan, Peng, Lirong, Seto, Edward
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573710/
https://ncbi.nlm.nih.gov/pubmed/26240284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00400-15
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