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Patient mutation directed shRNA screen uncovers novel bladder tumor growth suppressors

Next generation sequencing (NGS) of human bladder cancer has revealed many gene alterations compared with normal tissue, with most being predicted to be “loss of function”. However, given the high number of alterations, evaluating the functional impact of each is impractical. Here we develop and use...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Hensel, Jonathan, Duex, Jason E., Owens, Charles, Dancik, Garrett M., Edwards, Michael G., Frierson, Henry F., Theodorescu, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573363/
https://ncbi.nlm.nih.gov/pubmed/26078295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0130
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