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Astrocytes Protect Against Isoflurane Neurotoxicity by Buffering pro Brain-Derived Neurotrophic Factor

BACKGROUND: Isoflurane induces cell death in neurons undergoing synaptogenesis via increased production of pro-brain derived neurotrophic factor (proBDNF) and activation of post-synaptic p75 neurotrophin receptor (p75(NTR)). Astrocytes express p75(NTR) but their role in neuronal p75(NTR) mediated ce...

詳細記述

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書誌詳細
出版年:Anesthesiology
主要な著者: Stary, Creed M., Sun, Xiaoyun, Giffard, Rona G.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573311/
https://ncbi.nlm.nih.gov/pubmed/26270940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000824
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