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Astrocytes Protect Against Isoflurane Neurotoxicity by Buffering pro Brain-Derived Neurotrophic Factor
BACKGROUND: Isoflurane induces cell death in neurons undergoing synaptogenesis via increased production of pro-brain derived neurotrophic factor (proBDNF) and activation of post-synaptic p75 neurotrophin receptor (p75(NTR)). Astrocytes express p75(NTR) but their role in neuronal p75(NTR) mediated ce...
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| 出版年: | Anesthesiology |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4573311/ https://ncbi.nlm.nih.gov/pubmed/26270940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000824 |
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