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Astrocytes Protect Against Isoflurane Neurotoxicity by Buffering pro Brain-Derived Neurotrophic Factor
BACKGROUND: Isoflurane induces cell death in neurons undergoing synaptogenesis via increased production of pro-brain derived neurotrophic factor (proBDNF) and activation of post-synaptic p75 neurotrophin receptor (p75(NTR)). Astrocytes express p75(NTR) but their role in neuronal p75(NTR) mediated ce...
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| Publicado no: | Anesthesiology |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4573311/ https://ncbi.nlm.nih.gov/pubmed/26270940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000824 |
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