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Leflunomide attenuates hepatocyte injury by inhibiting Kupffer cells

AIM: To investigate the importance of direct contact between Kupffer cells (KCs) and hepatocytes (HCs) during hepatic inflammatory responses, and the effect of leflunomide’s active metabolite, A(771726), on cytokines in KCs, HCs and KC cocultures (DC cocultures). METHODS: KCs and HCs in liver were i...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Yao, Hong-Wei, Li, Jun, Chen, Ji-Qiang, Xu, Shu-Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572763/
https://ncbi.nlm.nih.gov/pubmed/15162534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i11.1608
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