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Leflunomide attenuates hepatocyte injury by inhibiting Kupffer cells

AIM: To investigate the importance of direct contact between Kupffer cells (KCs) and hepatocytes (HCs) during hepatic inflammatory responses, and the effect of leflunomide’s active metabolite, A(771726), on cytokines in KCs, HCs and KC cocultures (DC cocultures). METHODS: KCs and HCs in liver were i...

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Bibliografske podrobnosti
izdano v:World J Gastroenterol
Main Authors: Yao, Hong-Wei, Li, Jun, Chen, Ji-Qiang, Xu, Shu-Yun
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Inc 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572763/
https://ncbi.nlm.nih.gov/pubmed/15162534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i11.1608
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