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Leflunomide attenuates hepatocyte injury by inhibiting Kupffer cells

AIM: To investigate the importance of direct contact between Kupffer cells (KCs) and hepatocytes (HCs) during hepatic inflammatory responses, and the effect of leflunomide’s active metabolite, A(771726), on cytokines in KCs, HCs and KC cocultures (DC cocultures). METHODS: KCs and HCs in liver were i...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:World J Gastroenterol
Asıl Yazarlar: Yao, Hong-Wei, Li, Jun, Chen, Ji-Qiang, Xu, Shu-Yun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Baishideng Publishing Group Inc 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572763/
https://ncbi.nlm.nih.gov/pubmed/15162534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i11.1608
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