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Leflunomide attenuates hepatocyte injury by inhibiting Kupffer cells
AIM: To investigate the importance of direct contact between Kupffer cells (KCs) and hepatocytes (HCs) during hepatic inflammatory responses, and the effect of leflunomide’s active metabolite, A(771726), on cytokines in KCs, HCs and KC cocultures (DC cocultures). METHODS: KCs and HCs in liver were i...
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| Опубликовано в: : | World J Gastroenterol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Baishideng Publishing Group Inc
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4572763/ https://ncbi.nlm.nih.gov/pubmed/15162534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i11.1608 |
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