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Protonation of Glu(135) Facilitates the Outward-to-Inward Structural Transition of Fucose Transporter
Major facilitator superfamily (MFS) transporters typically need to alternatingly sample the outward-facing and inward-facing conformations, in order to transport the substrate across membrane. To understand the mechanism, in this work, we focused on one MFS member, the L-fucose/H(+) symporter (FucP)...
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| Publicado no: | Biophys J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4572579/ https://ncbi.nlm.nih.gov/pubmed/26244736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.06.037 |
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