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Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin

In vertebrates, the iron exporter ferroportin releases Fe(2+) from cells into plasma, thereby maintaining iron homeostasis. The transport activity of ferroportin is suppressed by the peptide hormone hepcidin, which exhibits upregulated expression in chronic inflammation, causing iron-restrictive ana...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Taniguchi, Reiya, Kato, Hideaki E., Font, Josep, Deshpande, Chandrika N., Wada, Miki, Ito, Koichi, Ishitani, Ryuichiro, Jormakka, Mika, Nureki, Osamu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Pub. Group 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633820/
https://ncbi.nlm.nih.gov/pubmed/26461048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9545
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