Calcium is an essential cofactor for metal efflux by the ferroportin transporter family

Ferroportin (Fpn)—the only known cellular iron exporter—transports dietary and recycled iron into the blood plasma, and transfers iron across the placenta. Despite its central role in iron metabolism, our molecular understanding of Fpn-mediated iron efflux remains incomplete. Here, we report that Ca...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Deshpande, Chandrika N., Ruwe, T. Alex, Shawki, Ali, Xin, Vicky, Vieth, Kyle R., Valore, Erika V., Qiao, Bo, Ganz, Tomas, Nemeth, Elizabeta, Mackenzie, Bryan, Jormakka, Mika
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079014/
https://ncbi.nlm.nih.gov/pubmed/30082682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05446-4
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