Conformational Transitions in the Glycine-Bound GluN1 NMDA Receptor LBD via Single-Molecule FRET

The N-methyl-D-aspartate receptor (NMDAR) is a member of the glutamate receptor family of proteins and is responsible for excitatory transmission. Activation of the receptor is thought to be controlled by conformational changes in the ligand binding domain (LBD); however, glutamate receptor LBDs can...

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Vydáno v:Biophys J
Hlavní autoři: Cooper, David R., Dolino, Drew M., Jaurich, Henriette, Shuang, Bo, Ramaswamy, Swarna, Nurik, Caitlin E., Chen, Jixin, Jayaraman, Vasanthi, Landes, Christy F.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2015
Témata:
Channels and Transporters
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572502/
https://ncbi.nlm.nih.gov/pubmed/26153703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.05.025
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