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Rett syndrome: disruption of epigenetic control of postnatal neurological functions

Loss-of-function mutations in the X-linked gene Methyl-CpG-binding protein 2 (MECP2) cause a devastating pediatric neurological disorder called Rett syndrome. In males, these mutations typically result in severe neonatal encephalopathy and early lethality. On the other hand, owing to expression of t...

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Publicado en:Hum Mol Genet
Autores principales: Pohodich, Amy E., Zoghbi, Huda Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571996/
https://ncbi.nlm.nih.gov/pubmed/26060191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv217
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