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Impaired spatial memory codes in a mouse model of Rett syndrome

The Mecp2(+/-) mouse model recapitulates many phenotypes of patients with Rett syndrome (RTT), including learning and memory deficits. It is unknown, however, how the disease state alters memory circuit functions in vivo in RTT mice. Here we recorded from hippocampal place cells, which are thought t...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Kee, Sara E, Mou, Xiang, Zoghbi, Huda Y, Ji, Daoyun
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054527/
https://ncbi.nlm.nih.gov/pubmed/30028675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31451
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