A Metabolic Shift toward Pentose Phosphate Pathway Is Necessary for Amyloid Fibril- and Phorbol 12-Myristate 13-Acetate-induced Neutrophil Extracellular Trap (NET) Formation

Neutrophils are the main defense cells of the innate immune system. Upon stimulation, neutrophils release their chromosomal DNA to trap and kill microorganisms and inhibit their dissemination. These chromatin traps are termed neutrophil extracellular traps (NETs) and are decorated with granular and...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Azevedo, Estefania P., Rochael, Natalia C., Guimarães-Costa, Anderson B., de Souza-Vieira, Thiago S., Ganilho, Juliana, Saraiva, Elvira M., Palhano, Fernando L., Foguel, Debora
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571968/
https://ncbi.nlm.nih.gov/pubmed/26198639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.640094
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