DNA supercoiling and the leu-500 promoter mutation of Salmonella typhimurium.

DNA supercoiling is an important, but relatively poorly understood factor which influences promoter function. leu-500 is a point mutation in the promoter of the leucine operon of Salmonella typhimurium which confers leucine auxotrophy. It can be phenotypically suppressed by mutations in the topA gen...

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Bibliographic Details
Main Authors: Richardson, S M, Higgins, C F, Lilley, D M
Format: Artigo
Language:Inglês
Published: 1988
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC457179/
https://ncbi.nlm.nih.gov/pubmed/2844526
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