Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits

SHANK3 (also known as PROSAP2) is a postsynaptic scaffolding protein at excitatory synapses in which mutations and deletions have been implicated in patients with idiopathic autism, Phelan–McDermid (aka 22q13 microdeletion) syndrome, and other neuropsychiatric disorders. In this study, we have creat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Speed, Haley E., Kouser, Mehreen, Xuan, Zhong, Reimers, Jeremy M., Ochoa, Christine F., Gupta, Natasha, Liu, Shunan, Powell, Craig M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571502/
https://ncbi.nlm.nih.gov/pubmed/26134648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3125-14.2015
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados