Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits

SHANK3 (also known as PROSAP2) is a postsynaptic scaffolding protein at excitatory synapses in which mutations and deletions have been implicated in patients with idiopathic autism, Phelan–McDermid (aka 22q13 microdeletion) syndrome, and other neuropsychiatric disorders. In this study, we have creat...

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Argitaratua izan da:J Neurosci
Egile Nagusiak: Speed, Haley E., Kouser, Mehreen, Xuan, Zhong, Reimers, Jeremy M., Ochoa, Christine F., Gupta, Natasha, Liu, Shunan, Powell, Craig M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2015
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Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571502/
https://ncbi.nlm.nih.gov/pubmed/26134648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3125-14.2015
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