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Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude

Due to its distinct pharmacological profile and lower incidence of adverse events compared with other opioids, buprenorphine is considered a safe option for pain and substitution therapy. However, despite its wide clinical use, little is known about the synaptic effects of buprenorphine in nocicepti...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gerhold, Katharina J., Drdla-Schutting, Ruth, Honsek, Silke D., Forsthuber, Liesbeth, Sandkühler, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571500/
https://ncbi.nlm.nih.gov/pubmed/26134641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0731-14.2015
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