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Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude

Due to its distinct pharmacological profile and lower incidence of adverse events compared with other opioids, buprenorphine is considered a safe option for pain and substitution therapy. However, despite its wide clinical use, little is known about the synaptic effects of buprenorphine in nocicepti...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Gerhold, Katharina J., Drdla-Schutting, Ruth, Honsek, Silke D., Forsthuber, Liesbeth, Sandkühler, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571500/
https://ncbi.nlm.nih.gov/pubmed/26134641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0731-14.2015
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