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Distinct Mechanisms Underlying Pronociceptive Effects of Opioids
In addition to analgesia, opioids may also produce paradoxical pain amplification [opioid-induced hyperalgesia (OIH)] either on abrupt withdrawal or during continuous long-term application. Here, we assessed antinociceptive and pronociceptive effects of three clinically used opioids at C-fiber synap...
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| Publicado en: | J Neurosci |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Society for Neuroscience
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6633307/ https://ncbi.nlm.nih.gov/pubmed/22090501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3491-11.2011 |
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