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Distinct Mechanisms Underlying Pronociceptive Effects of Opioids

In addition to analgesia, opioids may also produce paradoxical pain amplification [opioid-induced hyperalgesia (OIH)] either on abrupt withdrawal or during continuous long-term application. Here, we assessed antinociceptive and pronociceptive effects of three clinically used opioids at C-fiber synap...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Heinl, Céline, Drdla-Schutting, Ruth, Xanthos, Dimitris N., Sandkühler, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633307/
https://ncbi.nlm.nih.gov/pubmed/22090501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3491-11.2011
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