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Complement 3a receptor in dorsal horn microglia mediates pronociceptive neuropeptide signaling

The complement 3a receptor (C3aR1) participates in microglial signaling under pathological conditions and was recently shown to be activated by the neuropeptide TLQP-21. We previously demonstrated that TLQP-21 elicits hyperalgesia and contributes to nerve injury-induced hypersensitivity through an u...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Doolen, Suzanne, Cook, Jennifer, Riedl, Maureen, Kitto, Kelley, Kohsaka, Shinichi, Honda, Christopher N., Fairbanks, Carolyn A., Taylor, Bradley K., Vulchanova, Lucy
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747931/
https://ncbi.nlm.nih.gov/pubmed/28850719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23208
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