Complement 3a receptor in dorsal horn microglia mediates pronociceptive neuropeptide signaling

The complement 3a receptor (C3aR1) participates in microglial signaling under pathological conditions and was recently shown to be activated by the neuropeptide TLQP-21. We previously demonstrated that TLQP-21 elicits hyperalgesia and contributes to nerve injury-induced hypersensitivity through an u...

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Udgivet i:Glia
Main Authors: Doolen, Suzanne, Cook, Jennifer, Riedl, Maureen, Kitto, Kelley, Kohsaka, Shinichi, Honda, Christopher N., Fairbanks, Carolyn A., Taylor, Bradley K., Vulchanova, Lucy
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747931/
https://ncbi.nlm.nih.gov/pubmed/28850719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23208
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