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How Leiomodin and Tropomodulin use a common fold for different actin assembly functions
How proteins sharing a common fold have evolved different functions is a fundamental question in biology. Tropomodulins (Tmods) are prototypical actin filament pointed-end-capping proteins, whereas their homologues, Leiomodins (Lmods), are powerful filament nucleators. We show that Tmods and Lmods d...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Pub. Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4571291/ https://ncbi.nlm.nih.gov/pubmed/26370058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9314 |
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