Microconstriction Arrays for High-Throughput Quantitative Measurements of Cell Mechanical Properties

We describe a method for quantifying the mechanical properties of cells in suspension with a microfluidic device consisting of a parallel array of micron-sized constrictions. Using a high-speed charge-coupled device camera, we measure the flow speed, cell deformation, and entry time into the constri...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biophys J
Main Authors: Lange, Janina R., Steinwachs, Julian, Kolb, Thorsten, Lautscham, Lena A., Harder, Irina, Whyte, Graeme, Fabry, Ben
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2015
Teme:
Cell Biophysics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571004/
https://ncbi.nlm.nih.gov/pubmed/26153699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.05.029
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