Unbiased High-Precision Cell Mechanical Measurements with Microconstrictions

We describe a quantitative, high-precision, high-throughput method for measuring the mechanical properties of cells in suspension with a microfluidic device, and for relating cell mechanical responses to protein expression levels. Using a high-speed (750 fps) charge-coupled device camera, we measure...

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Bibliographic Details
Published in:Biophys J
Main Authors: Lange, Janina R., Metzner, Claus, Richter, Sebastian, Schneider, Werner, Spermann, Monika, Kolb, Thorsten, Whyte, Graeme, Fabry, Ben
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2017
Subjects:
Cell Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389962/
https://ncbi.nlm.nih.gov/pubmed/28402889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.02.018
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