Transcriptional profiling of differentially vulnerable motor neurons at pre-symptomatic stage in the Smn(2b/-) mouse model of spinal muscular atrophy

INTRODUCTION: The term motor neuron disease encompasses a spectrum of disorders in which motor neurons are the lost. Importantly, while some motor neurons are lost early in disease and others remain intact at disease end-stage. This creates a valuable experimental paradigm to investigate the factors...

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Détails bibliographiques
Publié dans:Acta Neuropathol Commun
Auteurs principaux: Murray, Lyndsay M., Beauvais, Ariane, Gibeault, Sabrina, Courtney, Natalie L., Kothary, Rashmi
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570693/
https://ncbi.nlm.nih.gov/pubmed/26374403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0231-1
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