Sequencing of Candidate Genes in Dominican Families Implicates Both Rare Exonic and Common Non-Exonic Variants for Carotid Intima-Media Thickness at Bifurcation

BACKGROUND: Through linkage and tagSNP-based association studies in 100 Dominican Republic (DR) families, we previously identified ANLN and AOAH (7p14.3) as candidate genes for carotid intima-media thickness at bifurcation (bIMT). METHODS AND RESULTS: Introns, exons and flanking regions of ANLN and...

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Bibliographic Details
Published in:Hum Genet
Main Authors: Wang, Liyong, Beecham, Ashley, Dueker, Nicole, Blanton, Susan H., Rundek, Tatjana, Sacco, Ralph L.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570583/
https://ncbi.nlm.nih.gov/pubmed/26319989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-015-1592-z
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