Targeted sequencing of linkage region in Dominican families implicates PRIMA1 and the SPATA7-PTPN21-ZC3H14-EML5-TTC8 locus in carotid-intima media thickness and atherosclerotic events

Carotid intima-media thickness (cIMT) is a subclinical marker for atherosclerosis. Previously, we reported a quantitative trait locus (QTL) for total cIMT on chromosome 14q and identified PRiMA1, FOXN3 and CCDC88C as candidate genes using a common variants (CVs)-based approach. Herein, we further ev...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Wang, Liyong, Dueker, Nicole, Beecham, Ashley, Blanton, Susan H., Sacco, Ralph L., Rundek, Tatjana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691113/
https://ncbi.nlm.nih.gov/pubmed/31406157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48186-1
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