Fine Mapping Study Reveals Novel Candidate Genes for Carotid Intima-Media Thickness in Dominican Families

BACKGROUND: Carotid intima-media thickness (CIMT) is a subclinical measure for atherosclerosis. Previously, we have mapped quantitative trait loci (QTLs) for CIMT to chromosomes 7p (MLOD=3.1) and to 14q (MLOD=2.3). We sought to identify the underlying genetic variants within those QTLs, METHODS AND...

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Main Authors: Wang, Liyong, Beecham, Ashley, Zhuo, Degen, Dong, Chuanhui, Blanton, Susan H., Rundek, Tatjana, Sacco, Ralph L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341091/
https://ncbi.nlm.nih.gov/pubmed/22423143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.111.961763
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