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A nanoparticle formula for delivering siRNA or miRNAs to tumor cells in cell culture and in vivo
To improve RNA delivery, we present a protocol to produce an RNA carrier based on a Zn(II)-dipicolylamine (Zn-DPA) analog, which is an artificial receptor for phosphate anion derivatives. We further functionalized this Zn-DPA analog to hyaluronic acid (HA)-based self-assembled nanoparticles (HA-NPS)...
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| Publicat a: | Nat Protoc |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4570470/ https://ncbi.nlm.nih.gov/pubmed/25033207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.128 |
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