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Dietary flavonoid fisetin binds to β-tubulin and disrupts microtubule dynamics in prostate cancer cells
Microtubule targeting based therapies have revolutionized cancer treatment; however, resistance and side effects remain a major limitation. Therefore, novel strategies that can overcome these limitations are urgently needed. We made a novel discovery that fisetin, a hydroxyflavone, is a microtubule...
Gardado en:
| Publicado en: | Cancer Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4570246/ https://ncbi.nlm.nih.gov/pubmed/26235140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.07.030 |
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