MtDNA segregation in heteroplasmic tissues is common in vivo and modulated by haplotype differences and developmental stage

The dynamics by which mitochondrial DNA (mtDNA) evolves within organisms are still poorly understood, despite the fact that inheritance and proliferation of mutated mtDNA causes fatal and incurable diseases. When two mtDNA haplotypes are present in a cell, it is usually assumed that segregation (the...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Burgstaller, Joerg Patrick, Johnston, Iain G., Jones, Nick S., Albrechtová, Jana, Kolbe, Thomas, Vogl, Claus, Futschik, Andreas, Mayrhofer, Corina, Klein, Dieter, Sabitzer, Sonja, Blattner, Mirjam, Gülly, Christian, Poulton, Joanna, Rülicke, Thomas, Piálek, Jaroslav, Steinborn, Ralf, Brem, Gottfried
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570183/
https://ncbi.nlm.nih.gov/pubmed/24910436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.05.020
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars