Anti-proliferative and pro-apoptotic activity of GD2 ganglioside-specific monoclonal antibody 3F8 in human melanoma cells

The beneficial clinical effects of immunotherapy with GD2-specific monoclonal antibodies (mAbs) in melanoma and neuroblastoma patients have stimulated interest in characterizing the mechanisms underlying their antitumor effects. Previous studies have shown that GD2-specific mAbs mediate complement-...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Tsao, Chun-Yen, Sabbatino, Francesco, Cheung, Nai-Kong V, Hsu, Jeff Chi-feng, Villani, Vincenzo, Wang, Xinhui, Ferrone, Soldano
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570105/
https://ncbi.nlm.nih.gov/pubmed/26405581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1023975
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