Peptides mimicking GD2 ganglioside elicit cellular, humoral and tumor-protective immune responses in mice

INTRODUCTION: Because of its restricted distribution in normal tissues and its high expression on tumors of neuroectodermal origin, GD2 ganglioside is an excellent target for active specific immunotherapy. However, GD2 usually elicits low-titered IgM and no IgG or cellular immune responses, limiting...

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Main Authors: Wondimu, Assefa, Zhang, Tianqian, Kieber-Emmons, Thomas, Gimotty, Phyllis, Sproesser, Katrin, Somasundaram, Rajasekharan, Ferrone, Soldano, Tsao, Chun-Yen, Herlyn, Dorothee
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426288/
https://ncbi.nlm.nih.gov/pubmed/18157673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-007-0439-4
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