Spatiotemporal regulation of cAMP signaling controls the human trophoblast fusion

During human placentation, mononuclear cytotrophoblasts fuse to form multinucleated syncytia ensuring hormonal production and nutrient exchanges between the maternal and fetal circulation. Syncytial formation is essential for the maintenance of pregnancy and for fetal growth. The cAMP signaling path...

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Publicat a:Front Pharmacol
Autors principals: Gerbaud, Pascale, Taskén, Kjetil, Pidoux, Guillaume
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569887/
https://ncbi.nlm.nih.gov/pubmed/26441659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00202
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