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Spatiotemporal regulation of cAMP signaling controls the human trophoblast fusion

During human placentation, mononuclear cytotrophoblasts fuse to form multinucleated syncytia ensuring hormonal production and nutrient exchanges between the maternal and fetal circulation. Syncytial formation is essential for the maintenance of pregnancy and for fetal growth. The cAMP signaling path...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Gerbaud, Pascale, Taskén, Kjetil, Pidoux, Guillaume
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569887/
https://ncbi.nlm.nih.gov/pubmed/26441659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00202
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