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Spatiotemporal regulation of cAMP signaling controls the human trophoblast fusion

During human placentation, mononuclear cytotrophoblasts fuse to form multinucleated syncytia ensuring hormonal production and nutrient exchanges between the maternal and fetal circulation. Syncytial formation is essential for the maintenance of pregnancy and for fetal growth. The cAMP signaling path...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Gerbaud, Pascale, Taskén, Kjetil, Pidoux, Guillaume
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569887/
https://ncbi.nlm.nih.gov/pubmed/26441659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00202
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