Retinoic Acid Activity in Undifferentiated Neural Progenitors Is Sufficient to Fulfill Its Role in Restricting Fgf8 Expression for Somitogenesis

Bipotent axial stem cells residing in the caudal epiblast during late gastrulation generate neuroectodermal and presomitic mesodermal progeny that coordinate somitogenesis with neural tube formation, but the mechanism that controls these two fates is not fully understood. Retinoic acid (RA) restrict...

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Publicat a:PLoS One
Autors principals: Cunningham, Thomas J., Brade, Thomas, Sandell, Lisa L., Lewandoski, Mark, Trainor, Paul A., Colas, Alexandre, Mercola, Mark, Duester, Gregg
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569375/
https://ncbi.nlm.nih.gov/pubmed/26368825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137894
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